Familial hypercholesterolemia: screening, diagnosi... [J Clin Lipidol. 2011] - PubMed result

Familial hyperch*lesterolemia: screening, diagnosi...[J Clin Lipidol.2011] - PubMed result: "J Clin Lipidol.2011 Jun;5(3 Suppl):S1-8.Epub 2011 Apr 12.
Familial hyperch*lesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hyperch*lesterolemia.
Goldberg AC, Hopkins PN, Toth PP, Ballantyne CM, Rader DJ, Robinson JG, Daniels SR, Gidding SS, de Ferranti SD, Ito MK, McGowan MP, Moriarty PM, Cromwell WC, Ross JL, Ziajka PE.
Source
Washington University Medical School, St.Louis, MO, USA.agoldber@dom.wustl.edu

Abstract
The familial hyperch*lesterolemias (FH) are a group of genetic defects resulting in severe elevations of blood ch*lesterol levels and increased risk of premature coronary heart disease.FH is among the most commonly occurring congenital metabolic disorders.FH is a treatable disease.Aggressive lipid lowering is necessary to achieve the target LDL ch*lesterol reduction of at least 50% or more.Even greater target LDL ch*lesterol reductions may be necessary for FH patients who have other CHD risk factors.Despite the prevalence of this disease and the availability of effective treatment options, FH is both underdiagnosed and undertreated, particularly among children.Deficiencies in the diagnosis and treatment of FH indicate the need for greatly increased awareness and understanding of this disease, both on the part of the public and of healthcare practitioners.This document provides recommendations for the screening, diagnosis and treatment of FH in pediatric and adult patients developed by the National Lipid Association Expert Panel on Familial Hyperch*lesterolemia.This report goes beyond previously published guidelines by providing specific clinical guidance for the primary care clinician and lipid specialist with the goal of improving care of patients with FH and reducing their elevated risk for CHD.

Copyright В© 2011 National Lipid Association.Published by Elsevier Inc.All rights reserved.

PMID: 21600525
[PubMed - in process]

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